Synthesis of Aminooxy End-Functionalized pNIPAAm by RAFT Polymerization for Protein and Polysaccharide Conjugation
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چکیده
منابع مشابه
Synthesis of the tumor associative α-aminooxy disaccharide of the TF antigen and its conjugation to a polysaccharide immune stimulant.
The α-aminooxy derivative of the Thomsen-Friedenriech tumor associated carbohydrate antigen has been synthesized in 11 steps utilizing a D-GalN3 acceptor carrying a pre-installed α-N-hydroxysuccinimidyl moiety. The natural α linkage was prepared in high selectivity employing a suitably protected D-GalN3-thioglycoside donor with N-hydroxysuccinimide. With access to α-TF-ONH2, the preparation of ...
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ژورنال
عنوان ژورنال: Macromolecules
سال: 2009
ISSN: 0024-9297,1520-5835
DOI: 10.1021/ma9013803